Oxidative Load and Cancer: Understanding the Metabolic Links to Prevention and Progression

This course examines the critical role of oxidative load in driving metabolic dysfunction, cancer initiation, and cancer progression. We will explore how chronic oxidative stress disrupts cellular signaling, damages DNA, impairs mitochondrial function, and alters key metabolic pathways, creating an environment favorable to carcinogenesis. We will also investigate the concept of hormetic stress such as exercise, fasting, phytochemicals, and thermal stress intervention—that can activate adaptive cellular defense mechanisms and enhance resilience against oxidative damage. The course will highlight evidence-based strategies for assessing oxidative burden and hormetic capacity in patients, including relevant laboratory markers, and will cover clinical interventions—such as nutritional, lifestyle, and nutraceutical approaches—that help reduce maladaptive oxidative stress while promoting beneficial hormetic adaptation.

Learning Objectives

  1. Explain the biochemical mechanisms by which oxidative load contributes to metabolic dysfunction and cancer development.
  2. Identify laboratory markers used to assess oxidative stress, antioxidant capacity, and adaptive hormetic responses in clinical practice.

 

Sponsor Biotics Research Corporation

 

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